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KMID : 1001020160140020082
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Korean Journal of Urological Oncology
2016 Volume.14 No. 2 p.82 ~ p.87
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Thrombotic Thrombocytopenic Purpura Associated with Bone Marrow Necrosis Complicating Metastatic Extra-Mammary Paget's Disease
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Sohn Jong-Min
Lee Jae-Lyun
Kim Bum-Jun
Song Kyung-Mee
Cho Young-Uk
Kim Eun-Na
Hong Jun-Hyuck
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Abstract
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As extra-mammary Paget’s disease is rare and usually diagnosed at early stage when it is highly curable with surgical resection, it is much rarer to see patients with recurrent metastatic disease. Thrombotic thrombocytopenic purpura in patients with metastatic solid cancer is also a rare disease and may result from bone marrow metastasis or bone marrow necrosis. For the latter, the majority of cases are not eligible for systemic chemotherapy for rapid disease progression and poor performance status. Herein, authors report a patient with thrombotic thrombocytopenic purpura associated with bone marrow necrosis complicating extra-mammary Paget's disease who was successfully treated with docetaxel and carboplatin combination chemotherapy. (Korean J Urol Oncol 2016;14:82-87)
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KEYWORD
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Extramammary Paget’s disease, Bone marrow necrosis, Thrombotic thrombocytopenic purpura
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